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VSTM1 regulates monocyte/macrophage function via the NF-κB signaling pathway
- Source :
- Open Medicine, Vol 16, Iss 1, Pp 1513-1524 (2021)
- Publication Year :
- 2021
- Publisher :
- De Gruyter, 2021.
-
Abstract
- V-set and transmembrane domain-containing protein 1 (VSTM1) is negatively correlated with inflammation. However, its effect on atherosclerosis (AS) remains largely unexplored. In this study, we aimed to assess the effect of VSTM1 on the biological function of human peripheral blood mononuclear cells /macrophages stimulated by oxidized low-density lipoprotein (ox-LDL).
- Subjects :
- vstm1
monocyte/macrophage
inflammation
atherosclerosis
nf-κb
Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 23915463 and 20210353
- Volume :
- 16
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Open Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.b6c073f744547be9cd59681b89a9bda
- Document Type :
- article
- Full Text :
- https://doi.org/10.1515/med-2021-0353