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VSTM1 regulates monocyte/macrophage function via the NF-κB signaling pathway

Authors :
Wang Xiao-Fei
En-Zhou
Li Dong-Jiu
Mao Cheng-Yu
He Qing
Zhang Jun-Feng
Fan Yu-Qi
Wang Chang-Qian
Source :
Open Medicine, Vol 16, Iss 1, Pp 1513-1524 (2021)
Publication Year :
2021
Publisher :
De Gruyter, 2021.

Abstract

V-set and transmembrane domain-containing protein 1 (VSTM1) is negatively correlated with inflammation. However, its effect on atherosclerosis (AS) remains largely unexplored. In this study, we aimed to assess the effect of VSTM1 on the biological function of human peripheral blood mononuclear cells /macrophages stimulated by oxidized low-density lipoprotein (ox-LDL).

Details

Language :
English
ISSN :
23915463 and 20210353
Volume :
16
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Open Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.b6c073f744547be9cd59681b89a9bda
Document Type :
article
Full Text :
https://doi.org/10.1515/med-2021-0353