Research progress of artificial blood

Artificial blood is a type of liquid preparation with oxygen-loading capacity and can temporarily substitute some function of blood. The developed artificial blood can be divided into four categories: artificial synthetic hemoglobin, artificial red blood cells made from natural hemoglobin, perfluorocarbons, and stem cell-differentiated red blood cells. This review focuses on the domestic and foreign research progress of artificial blood in recent years, and discusses its clinical application value, development trend, and future research, in order to provide new ideas to the development the artificial blood products and promote clinical application.