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Plasmon-enhanced stimulated Raman scattering microscopy with single-molecule detection sensitivity

Authors :
Cheng Zong
Ranjith Premasiri
Haonan Lin
Yimin Huang
Chi Zhang
Chen Yang
Bin Ren
Lawrence D. Ziegler
Ji-Xin Cheng
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Stimulated Raman scattering (SRS) microscopy enables label-free chemical imaging at high speed, but has been limited by low sensitivity. Here, the authors demonstrate plasmon-enhanced SRS microscopy and achieve single molecule detection sensitivity.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b5e9f3a19554469386c68684a6b552dd
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-13230-1