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Pluripotent anti-inflammatory immunomodulatory effects of papaverine against cerebral ischemic-reperfusion injury

Authors :
Shuang Guan
Qiong Liu
Hao Gu
Ying-ying Zhang
Peng-lu Wei
Yi-fei Qi
Jun Liu
Zhong Wang
Source :
Journal of Pharmacological Sciences, Vol 144, Iss 2, Pp 69-75 (2020)
Publication Year :
2020
Publisher :
Elsevier, 2020.

Abstract

The mechanism of the papaverine (PV) for the treatment of cerebral ischemia remains unclear. A total of 42 mice induced with focal cerebral ischemia were randomly divided into three groups: PV,baicalin (BA)and vehicle group. Both PV and BA could significantly reduce the ischemic infarct volume (P

Details

Language :
English
ISSN :
13478613
Volume :
144
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Journal of Pharmacological Sciences
Publication Type :
Academic Journal
Accession number :
edsdoj.b5b43c974fd3458cbef3178ace13bb64
Document Type :
article
Full Text :
https://doi.org/10.1016/j.jphs.2020.07.008