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Dissecting the importance and origin of circulating myokines in gastric cancer cachexia
- Source :
- Frontiers in Endocrinology, Vol 15 (2024)
- Publication Year :
- 2024
- Publisher :
- Frontiers Media S.A., 2024.
-
Abstract
- BackgroundSome experimental data suggest that myokines may play an important role in developing cancer-associated cachexia (CAC), but their relevance in humans remains poorly explored. In our study, we tested the hypothesis that circulating myokines are associated with the pathogenesis of CAC in a model population of gastric cancer.MethodsA group of 171 treatment naïve patients with adenocarcinoma of the stomach were prospectively examined. Cachexia was defined as weight loss >5% or weight loss >2% with either BMI
Details
- Language :
- English
- ISSN :
- 16642392
- Volume :
- 15
- Database :
- Directory of Open Access Journals
- Journal :
- Frontiers in Endocrinology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.b56776ea2ed046cfaf7f3d6a6df740d6
- Document Type :
- article
- Full Text :
- https://doi.org/10.3389/fendo.2024.1437197