Cellular imaging by targeted assembly of hot-spot SERS and photoacoustic nanoprobes using split-fluorescent protein scaffolds

Authors :: Tuğba Köker
Nathalie Tang
Chao Tian
Wei Zhang
Xueding Wang
Richard Martel
Fabien Pinaud
Source :: Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Publication Year :: 2018
Publisher :: Nature Portfolio, 2018.
Abstract: Traditional methods for the assembly of plasmonic nanoparticles into photo-responsive probes suffer from multiple problems. Here the authors use split fluorescent protein fragments as molecular glue to form stable nanoclusters for surface enhanced Raman scattering and photoacoustic imaging in live cells.

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