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Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse

Authors :
Andrea Ghisleni
Camilla Galli
Pascale Monzo
Flora Ascione
Marc-Antoine Fardin
Giorgio Scita
Qingsen Li
Paolo Maiuri
Nils C. Gauthier
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

The cell cortex that supports the plasma membrane contains spectrin, a protein that interacts with the acto-myosin cytoskeleton. Here, the authors analyze spectrin behavior during cellular mechanoresponse and membrane trafficking, and observe spectrin regulation by myosin-driven contractility.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b49028cf2ff84964a7c443b6f61b4c67
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-18825-7