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Comorbidity in trichotillomania (hair‐pulling disorder): A cluster analytical approach

Authors :
Christine Lochner
Nancy J. Keuthen
Erin E. Curley
Esther S. Tung
Sarah A. Redden
Emily J. Ricketts
Christopher C. Bauer
Douglas W. Woods
Jon E. Grant
Dan J. Stein
Source :
Brain and Behavior, Vol 9, Iss 12, Pp n/a-n/a (2019)
Publication Year :
2019
Publisher :
Wiley, 2019.

Abstract

Abstract Background A promising approach to reducing the phenotypic heterogeneity of psychiatric disorders involves the identification of homogeneous subtypes. Careful study of comorbidity in obsessive‐compulsive disorder (OCD) contributed to the identification of the DSM‐5 subtype of OCD with tics. Here we investigated one of the largest available cohorts of clinically diagnosed trichotillomania (TTM) to determine whether subtyping TTM based on comorbidity would help delineate clinically meaningful subgroups. Methods As part of an ongoing international collaboration, lifetime comorbidity data were collated from 304 adults with pathological hair‐pulling who fulfilled criteria for DSM‐IV‐TR or DSM‐5 TTM. Cluster analysis (Ward's method) based on comorbidities was undertaken. Results Three clusters were identified, namely Cluster 1: cases without any comorbidities (n = 63, 20.7%) labeled “simple TTM,” Cluster 2: cases with comorbid major depressive disorder only (N = 49, 16.12%) labeled “depressive TTM,” and Cluster 3: cases presenting with combinations of the investigated comorbidities (N = 192, 63.16%) labeled “complex TTM.” The clusters differed in terms of hair‐pulling severity (F = 3.75, p = .02; Kruskal–Wallis [KW] p

Details

Language :
English
ISSN :
21623279
Volume :
9
Issue :
12
Database :
Directory of Open Access Journals
Journal :
Brain and Behavior
Publication Type :
Academic Journal
Accession number :
edsdoj.b3eb233d05b049c884a68e9f26e73a40
Document Type :
article
Full Text :
https://doi.org/10.1002/brb3.1456