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De novo development of gliomas in a child with neurofibromatosis type 1, fragile X and previously normal brain magnetic resonance imaging
- Source :
- Radiology Case Reports, Vol 11, Iss 1, Pp 33-35 (2016)
- Publication Year :
- 2016
- Publisher :
- Elsevier, 2016.
-
Abstract
- Fifteen to 20% of children with neurofibromatosis type 1 develop low-grade glial neoplasms. However, since neuroimaging is not routinely obtained until a child is clinically symptomatic, little is known about presymptomatic radiographic characteristics of gliomas in this at-risk population. Herein, we describe a child with neurofibromatosis type 1 who initially had normal brain imaging before the development of multifocal gliomas. Comparison of these serial images demonstrated that brain tumors can arise de novo in children with this cancer predisposition syndrome, further underscoring the limited prognostic value of normal baseline magnetic resonance imaging.
Details
- Language :
- English
- ISSN :
- 19300433
- Volume :
- 11
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Radiology Case Reports
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.b3d4b1912958478fa28c2fdfb092a92b
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.radcr.2015.12.008