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ROR2 regulates self-renewal and maintenance of hair follicle stem cells

Authors :
Anthony Veltri
Christopher M. R. Lang
Gaia Cangiotti
Chim Kei Chan
Wen-Hui Lien
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Wnt signaling functions in tissue homeostasis and tumorigenesis. Here the authors show that ROR2, a Wnt receptor, plays roles not only in transducing Wnt signaling, but also in regulation of DNA damage response critical for stem cell maintenance.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b383d716f786422a92e3bc8bc8deba52
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-32239-7