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De novo main-chain modeling for EM maps using MAINMAST

Authors :
Genki Terashi
Daisuke Kihara
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Main-chain tracing remains a time-consuming task for medium resolution cryo-EM maps. Here the authors describe MAINMAST, a computational approach for building main-chain structure models of proteins from EM maps of 4-5 Å resolution that builds main-chain models of the protein by tracing local dense points in the density distribution.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b319603714d4b1b8150b89930cce550
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-04053-7