Predictive value of multi-parameter magnetic resonance imaging using vesical imaging-reporting and data system for muscle invasive in bladder cancer

Objective To evaluate the predictive value of vesical imaging-reporting and data system (VI-RADS) based on multi-parameter magnetic resonance imaging (MRI) for muscle invasive bladder cancer. Methods Clinical data of 278 patients undergoing transurethral resection of bladder tumor (TURBT) or radical cystectomy in our hospital from January 2017 to March 2021 were collected in this study. After VI-RADS score was assessed by 2 radiologists independently, Kappa test was used for the consistency of the obtained scores. Chi-square test was employed to analyze the consistency of VI-RADS score with pathological results. Receiver operating characteristic (ROC) curve was drawn to analyze the efficacy of VI-RADS scores in the diagnosis of muscle invasive bladder cancer. The consistency of VI-RADS score with pathological Results of tissues obtained by different surgical Methods was analyzed with Chi-square test. Results The VI-RADS scores of the 2 radiologists were consistent with each other (coincidence rate: 79.86%, kappa value: 0.750 8, P < 0.001). ROC curve analysis showed that the area under curve (AUC), Yodon index, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were 0.774, 54.78%, 96.16%, 58.62%, 58.14% and 96.23%, respectively, when predicting muscular invasion with VI-RADS score ≥3 as the threshold. The study also found that the coincidence rate between the pathological Results of radical cystectomy and VI-RADS score was 92.85%, which was significantly higher than that of TURBT (79.81%, P < 0.05). Conclusion VI-RADS score based on preoperative multi-parameter MRI has good consistency and stability, and is highly consistent with the Results of postoperative pathology. VI-RADS score ≥3 has predictive diagnostic value for muscular-invasive bladder cancer and can guide the selection of clinical surgical methods.