An overview of the most used synthetic pathways of 1,2,4-triazolo[1,5-a]pyrimidines

Among the all possible isomers of triazolopyrimidines, 1,2,4-triazolo[1,5-a]pyrimidines are the most important isomers owing to their vast activities in agriculture and medicinal chemistry. Herein, we present an overview of the most used synthetic pathways of this scaffold to assist researchers design new drug molecules with expected pharmacological activities