Back to Search
Start Over
Inulin Supplementation Reduces Systolic Blood Pressure in Women with Breast Cancer Undergoing Neoadjuvant Chemotherapy
- Source :
- Cardiovascular Therapeutics, Vol 2019 (2019)
- Publication Year :
- 2019
- Publisher :
- Hindawi-Wiley, 2019.
-
Abstract
- Introduction. Breast cancer is the most frequently diagnosed malignancy in women, and comorbidities like hypertension and obesity diminish their quality of life and negatively affect their response to chemotherapy. Furthermore, inulin supplementation is associated with the reduction of cardiovascular diseases (CVD) risk. Objective. To determine whether inulin supplementation prevents the elevation of blood pressure in women with breast cancer undergoing neoadjuvant therapy with cyclophosphamide and doxorubicin. Methods. This was a randomized, double-blind placebo controlled trial which included women with early-stage breast cancer undergoing neoadjuvant therapy (n=38). Patients were randomly assigned to participate in two different groups to receive either 15 g of inulin or 15 g of placebo (maltodextrin) for 21 days. Body composition and blood pressure were evaluated before and after the supplementation period. Results. Women in the inulin group showed a lower systolic blood pressure (SBP) after the supplementation (-4.21 mmHg, p
Details
- Language :
- English
- ISSN :
- 17555914 and 17555922
- Volume :
- 2019
- Database :
- Directory of Open Access Journals
- Journal :
- Cardiovascular Therapeutics
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.b2759dde2f0947f991e8dfdc94bed3c7
- Document Type :
- article
- Full Text :
- https://doi.org/10.1155/2019/5707150