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TRPM7 deficiency exacerbates cardiovascular and renal damage induced by aldosterone-salt

Authors :
Francisco J. Rios
Zhi-Guo Zou
Adam P. Harvey
Katie Y. Harvey
Livia L. Camargo
Karla B. Neves
Sarah E. F. Nichol
Rheure Alves-Lopes
Alexius Cheah
Maram Zahraa
Alexey G. Ryazanov
Lillia Ryazanova
Thomas Gudermann
Vladimir Chubanov
Augusto C. Montezano
Rhian M. Touyz
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Deficiency of the Mg2+-permeable channel/α-kinase TRPM7 in mice increases susceptibility to cardiovascular and renal fibrosis induced by aldosterone and salt.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.b2321b1b4554eefad7adf3bec82bdc7
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03715-z