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Translation regulatory factor BZW1 regulates preimplantation embryo development and compaction by restricting global non-AUG Initiation
- Source :
- Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Portfolio, 2022.
-
Abstract
- It is unclear how translational efficiency and codon stringency affect zygotic genome activation and early embryonic development. Here they show that the zygotic gene BZW1 increases start codon stringency, which is important for preimplantation development.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723 and 80610390
- Volume :
- 13
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.b1f151c5f5904dd9b80610390a7f96b6
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-022-34427-x