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Cross-species oncogenic signatures of breast cancer in canine mammary tumors

Authors :
Tae-Min Kim
In Seok Yang
Byung-Joon Seung
Sejoon Lee
Dohyun Kim
Yoo-Jin Ha
Mi-kyoung Seo
Ka-Kyung Kim
Hyun Seok Kim
Jae-Ho Cheong
Jung-Hyang Sur
Hojung Nam
Sangwoo Kim
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Comparison of spontaneous canine cancers and human cancers may illuminate future therapeutic avenues. Here, genomic analyses of these tumors highlights a convergence on PI3K-Akt oncogenic pathways.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b1a0a9b68044115ac3ec182334e71fc
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-17458-0