Back to Search Start Over

Genetic factors influencing HIV entry into target cells

Authors :
R. M. Khaitov
L. P. Alexeev
I. A. Kofiadi
G. O. Gudima
Source :
Бюллетень сибирской медицины, Vol 18, Iss 1, Pp 131-141 (2019)
Publication Year :
2019
Publisher :
Siberian State Medical University (Tomsk), 2019.

Abstract

Succeptibility to HIV and the dynamics of HIV infection progression to AIDS are dependent on unique individual factors. Revealing genetic features of natural resistance to HIV infection is of great importance for the development of effective strategies for disease control. This review presents an analysis of host gene alleles coding receptors and their ligands participating in viral entrance to target cell. These allelic variants and their combinations can have a significant influence on the individual resistance/sensitivity to HIV infection and may be associated with the HIV infection progression to AIDS.

Details

Language :
English, Russian
ISSN :
16820363 and 18193684
Volume :
18
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Бюллетень сибирской медицины
Publication Type :
Academic Journal
Accession number :
edsdoj.b16336cecd444e05920249547bad227b
Document Type :
article
Full Text :
https://doi.org/10.20538/1682-0363-2019-1-131-141