Back to Search
Start Over
Pharmacological EZH2 inhibition combined with retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells
- Source :
- Clinical Epigenetics, Vol 15, Iss 1, Pp 1-16 (2023)
- Publication Year :
- 2023
- Publisher :
- BMC, 2023.
-
Abstract
- Abstract Background Rhabdomyosarcomas (RMS) are predominantly paediatric sarcomas thought to originate from muscle precursor cells due to impaired myogenic differentiation. Despite intensive treatment, 5-year survival for patients with advanced disease remains low (
Details
- Language :
- English
- ISSN :
- 18687083
- Volume :
- 15
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Clinical Epigenetics
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.b09403c2536c486da89cc39dfaf84132
- Document Type :
- article
- Full Text :
- https://doi.org/10.1186/s13148-023-01583-w