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A mathematical model for exchanging waves between cellular DNA and drug molecules and their roles in curing cancer

Authors :
S.K. Elagan
Saad J. Almalki
M.R. Alharthi
Mohamed S. Mohamed
Mohamed F. El-Badawy
Source :
Results in Physics, Vol 22, Iss , Pp 103868- (2021)
Publication Year :
2021
Publisher :
Elsevier, 2021.

Abstract

DNA could emit some waves and absorb or repel drugs. Thus, DNA waves have the main role in drug’s effects on cells. Recently, some scientists have shown that the probability for survival in patients who taken nivolumab plus ipilimumab is more than in patients who obtained ipilimumab alone. We show that the reason for these events is that some drug molecules which have more charges could be absorbed more by charges on DNA within cells. We propose a physical model for calculating the attractive forces between drugs and DNA within cells. In this model, a drug is formed from charged particles and by its motions along blood vessels, some electrical currents are emerged. From other side, DNA within cells are also formed from charged particles. Charges of DNA within cells interact with charges of drugs and consequently; DNA within cells vibrate. Consequently, a cellular current is emerged which interacts with drug currents and two electrical and magnetical forces are emerged. We show that by increasing number of charged atoms within drugs and DNA, the attractive forces between cells and drugs increase. Thus, a system which is formed from two drugs like nivolumab plus ipilimumab includes more charges respect to one drug like ipilimumab alone. Consequently, this combination is more absorbed by charges on DNA within cells and is more effective. This could be generalized to any other drug that can be used in curing cancers.

Details

Language :
English
ISSN :
22113797
Volume :
22
Issue :
103868-
Database :
Directory of Open Access Journals
Journal :
Results in Physics
Publication Type :
Academic Journal
Accession number :
edsdoj.b052778c67154a2192fa7993f7fffee9
Document Type :
article
Full Text :
https://doi.org/10.1016/j.rinp.2021.103868