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Investigation of the Relationship between MR-Based Supraclavicular Fat Fraction and Thyroid Hormones
- Source :
- Obesity Facts, Vol 13, Iss 3, Pp 331-343 (2020)
- Publication Year :
- 2020
- Publisher :
- Karger Publishers, 2020.
-
Abstract
- Purpose: Brown adipose tissue (BAT) plays a potential role in energy and glucose metabolism in humans. Thyroid hormones (TH) are main regulators of BAT development and function. However, it remains unknown how the magnetic resonance (MR)-based proton density fat fraction (PDFF) of supraclavicular adipose tissue used as a surrogate marker for BAT presence relates to TH. Therefore, the purpose of this analysis was to investigate the relationship between supraclavicular PDFF and serum levels of TH. Methods: In total, 96 adult volunteers from a large cross-sectional study who underwent additional MR examination of the neck and pelvis were included in this analysis. Segmented PDFF maps of the supraclavicular and gluteal subcutaneous adipose tissue were generated. Delta PDFF was calculated as the difference between gluteal and supraclavicular PDFF and grouped as high (≥12%) or low (
Details
- Language :
- English
- ISSN :
- 16624025 and 16624033
- Volume :
- 13
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Obesity Facts
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.9ed7db8b403f4d9da20c42ae1b6b5dbf
- Document Type :
- article
- Full Text :
- https://doi.org/10.1159/000507294