Treatment Strategies for Congenital Diaphragmatic Hernia: Change Sometimes Comes Bearing Gifts

ObjectiveTo report treatment strategies’ evolution and its impact on congenital diaphragmatic hernia (CDH) outcome.DesignRegistry-based cohort study using the CDH Study Group database, 1995–2013.SettingInternational multicenter database.PatientsCDH patients entered into the registry. Late presenters or patients with very incomplete data were excluded. Patients were divided into three Eras (1995–2000; 2001–2006; 2007–2013).Main outcome measuresTreatment strategies and outcomes. One-way ANOVA, X2 test, and X2 test for trend were used. A Sydak-adjusted p