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Genome-wide fine-mapping identifies pleiotropic and functional variants that predict many traits across global cattle populations

Authors :
Ruidong Xiang
Iona M. MacLeod
Hans D. Daetwyler
Gerben de Jong
Erin O’Connor
Chris Schrooten
Amanda J. Chamberlain
Michael E. Goddard
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Genomic prediction of phenotype may be improved by using DNA mutations with functional, evolutionary, and pleiotropic consequences. Here the authors describe a method for genome-wide fine-mapping of QTLs and develop a genotyping array for improved prediction of genetic values for cattle traits.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.9ad0efaecc5840e095d958c5c857b6d5
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-21001-0