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Comparison between adult and foetal adnexa derived equine post-natal mesenchymal stem cells

Authors :
B. Merlo
G. Teti
A. Lanci
J. Burk
E. Mazzotti
M. Falconi
E. Iacono
Source :
BMC Veterinary Research, Vol 15, Iss 1, Pp 1-15 (2019)
Publication Year :
2019
Publisher :
BMC, 2019.

Abstract

Abstract Background Little is known about the differences among adult and foetal equine mesenchymal stem cells (MSCs), and no data exist about their comparative ultrastructural morphology. The aim of this study was to describe and compare characteristics, immune properties, and ultrastructural morphology of equine adult (bone marrow: BM, and adipose tissue: AT) and foetal adnexa derived (umbilical cord blood: UCB, and Wharton’s jelly: WJ) MSCs. Results No differences were observed in proliferation during the first 3 passages. While migration ability was similar among cells, foetal MSCs showed a higher adhesion ability, forming smaller spheroids after hanging drop culture (P

Details

Language :
English
ISSN :
17466148
Volume :
15
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Veterinary Research
Publication Type :
Academic Journal
Accession number :
edsdoj.9ab40f0d1f1b406fab32d0a8cf902058
Document Type :
article
Full Text :
https://doi.org/10.1186/s12917-019-2023-5