Back to Search Start Over

Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance

Authors :
Ankur Chakravarthy
Ian Reddin
Stephen Henderson
Cindy Dong
Nerissa Kirkwood
Maxmilan Jeyakumar
Daniela Rothschild Rodriguez
Natalia Gonzalez Martinez
Jacqueline McDermott
Xiaoping Su
Nagayasau Egawa
Christina S. Fjeldbo
Vilde Eide Skingen
Heidi Lyng
Mari Kyllesø Halle
Camilla Krakstad
Afschin Soleiman
Susanne Sprung
Matt Lechner
Peter J. I. Ellis
Mark Wass
Martin Michaelis
Heidi Fiegl
Helga Salvesen
Gareth J. Thomas
John Doorbar
Kerry Chester
Andrew Feber
Tim R. Fenton
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Human papillomavirus (HPV) is a known cause of cervical cancer. Here, the authors perform a multi-omic analysis using published cervical squamous cell carcinoma cohorts from the USA, Europe, and SubSaharan Africa and identify two cervical squamous cell carcinoma subtypes that display prognostic differences.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.9a5c4607e718467ca9be497358a18ce0
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-33544-x