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Synergistic insights into human health from aptamer- and antibody-based proteomic profiling

Authors :
Maik Pietzner
Eleanor Wheeler
Julia Carrasco-Zanini
Nicola D. Kerrison
Erin Oerton
Mine Koprulu
Jian’an Luan
Aroon D. Hingorani
Steve A. Williams
Nicholas J. Wareham
Claudia Langenberg
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Broad-capture affinity-based proteomic technologies inform how the readout of our genes affects human health. Here, the authors integrate aptamer- and antibody-based profiling to understand the mechanisms underlying gene-protein-disease associations.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.9a1bfa769147d886496493f0292435
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-27164-0