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Does Homeostasis Model Assessment of Insulin Resistance have a predictive value for post-coronary artery bypass grafting surgery outcomes?
- Source :
- Brazilian Journal of Cardiovascular Surgery, Vol 29, Iss 3, Pp 360-366 (2014)
- Publication Year :
- 2014
- Publisher :
- Sociedade Brasileira de Cirurgia Cardiovascular, 2014.
-
Abstract
- Objective: This study aims to investigate whether pre-operative Homeostasis Model Assessment Insulin Resistance (HOMA-IR) value is a predictor in non-diabetic coronary artery bypass grafting patients in combination with hemoglobin A1c, fasting blood glucose and insulin levels. Methods: Eighty one patients who were admitted to Cardiovascular Surgery Clinic at our hospital between August 2012 and January 2013 with a coronary artery bypass grafting indication were included. Patients were non-diabetic with 2.5, Group B; n=40), respectively. Pre-operative fasting blood glucose and insulin were measured and serum chemistry tests were performed. The Homeostasis Model Assessment Insulin Resistance values were calculated. Statistical analysis was performed. Results: There was a statistically significant difference in fasting blood glucose and HOMA-IR values between the groups. Cross-clamping time, and cardiopulmonary bypass time were longer in Group B, compared to Group A (P=0.043 and P=0.031, respectively). Logistic regression analysis revealed that hemoglobin A1c was not a reliable determinant factor alone for pre-operative glucometabolic evaluation of non-diabetic patients. The risk factors of fasting blood glucose and cardiopulmonary bypass time were more associated with high Homeostasis Model Assessment Insulin Resistance levels. Conclusion: Our study results suggest that preoperative screening of non-diabetic patients with Homeostasis Model Assessment Insulin Resistance may improve both follow-up visit schedule and short-term outcomes, and may be useful in risk stratification of the high-risk population for impending health problems.
Details
- Language :
- English
- ISSN :
- 16789741
- Volume :
- 29
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Brazilian Journal of Cardiovascular Surgery
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.9a01bc98973b42f3b6a6d8e7a8e0a338
- Document Type :
- article
- Full Text :
- https://doi.org/10.5935/1678-9741.20140105