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CELL RESPONSE TO INTRAPERITONEAL PDMS/HAP COMPOSITE IMPLANT

Authors :
Perica Vasiljević
Nenad Ignjatović
Miroslav Miljković
Vojin Savić
Ljubiša Đorđević
Stevo Najman
Dragan Uskoković
Source :
Acta Medica Medianae, Vol 44, Iss 3, Pp 5-8 (2005)
Publication Year :
2005
Publisher :
University in Nis, Faculty of Medicine, 2005.

Abstract

Siloxane polimers have been widely used in biomedicine and pharmacy due to their biocompatibility. Hydroxyapatite (HAp) is a natural constituent of bones, and therefore widely used in maxillofacial and orthopedic surgery. HAp itself is amorphous and without elasticity, so its characteristics can be improved when combined with organic polymers. We evaluated the interaction of cells and composites made of polydimethylsiloxane (PDMS) and HAp by scanning electron microscopy (SEM) 10 days after their intraperitoneal implantation into Balb/c mice. Two composites which were different in the quantity of HAp were analyzed. Both of them showed high adhesive characteristics for different cell types. The erythrocytes in cell clusters could be seen on the surface of the composite with higher quantity of HAp.

Details

Language :
English
ISSN :
03654478
Volume :
44
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Acta Medica Medianae
Publication Type :
Academic Journal
Accession number :
edsdoj.99ee56e3e2e4f20957754f2dbd1287a
Document Type :
article