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Visceral Adiposity and Its Impact on Nephrolithiasis: A Narrative Review

Authors :
Carlo Augusto Mallio
Laura Cea
Valerio D’Andrea
Andrea Buoso
Caterina Bernetti
Bruno Beomonte Zobel
Federico Greco
Source :
Journal of Clinical Medicine, Vol 13, Iss 14, p 4065 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

Kidney stones represent a serious medical problem, resulting from several factors such as diet, genetics, and certain medical conditions. Visceral adipose tissue has been shown in recent research to play a significant role in kidney stone formation, making it a more precise indicator than traditional obesity indicators such as body mass index. The main aim of this review is to summarize studies on visceral obesity as a predictive marker for nephrolithiasis and to highlight new mechanistic pathways such as adipokine-mediated inflammation and its impact on kidney stone formation. This review emphasizes the importance of considering visceral fat in the prevention and management of kidney stones, suggesting that targeted strategies to reduce visceral fat could decrease the incidence of kidney stones and their management costs. Further prospective studies are needed to validate these findings and propose preventive strategies based on visceral adiposity assessments.

Details

Language :
English
ISSN :
13144065 and 20770383
Volume :
13
Issue :
14
Database :
Directory of Open Access Journals
Journal :
Journal of Clinical Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.99b51428c8d94081b2ee08390c4b73eb
Document Type :
article
Full Text :
https://doi.org/10.3390/jcm13144065