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Parallel derivation of isogenic human primed and naive induced pluripotent stem cells
- Source :
- Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
- Publication Year :
- 2018
- Publisher :
- Nature Portfolio, 2018.
-
Abstract
- Derivation of human induced pluripotent stem cells (hiPSCs) produces primed hiPSCs that can in turn be converted to naive hiPSCs. Here, the authors directly reprogram somatic cells to form both naive and primed isogenic hiPSCs and confirm the similarity of naive hiPSCs to their in vivo counterparts.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723 and 03730743
- Volume :
- 9
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.99050a32ab984d7caf964c0d03730743
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-017-02107-w