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First single-center five-way kidney exchange cycle in India
- Source :
- Indian Journal of Transplantation, Vol 15, Iss 4, Pp 338-342 (2021)
- Publication Year :
- 2021
- Publisher :
- Wolters Kluwer Medknow Publications, 2021.
-
Abstract
- Objective: The logistical issues, limited resources, and surgical capacity are the challenges to simultaneous kidney exchange transplant surgeries in India. We report the first single-center 5-way nonsimultaneous kidney exchange cycle from India without donor renege. The challenges and solutions for the same are discussed. Methods: Five donor–recipient pairs (DRPs) participated in 5-way kidney exchange cycle after permission of Institutional and Gujarat State Level Authorization Committee for organ transplantation. Four DRP were ABO-incompatible and the fifth was compatible. Results: Two DRP were operated on November 22 and three on November 23, 2018. One bridge donor wait time was 1 day. All five recipients were discharged on November 30, 2018, without any medical or surgical complication; normal kidney allograft function and donor renege. We have increased chain length gradually from 2-way (June 2000), 3-way (February 2013), 4-way (April 2016), 5-way (November 2018), 6-way (February 2019), and 10-way (January 2020) in 440 kidney exchange transplants at our institute. We have used compatible pairs in gradually increasing chain length from 2-way (May 2012), 3-way (August 2013), 4-way (July 2018), 5-way (November 2018), and 6-way (February 2019) to increase transplant for difficult to match pairs. Conclusions: To the best of our knowledge, this is the first single-center 5-way kidney exchange cycle from India. Increasing chain length has the potential to offer better quality of matching and transplants rates for difficult-to-match pairs in kidney exchange.
Details
- Language :
- English
- ISSN :
- 22120017 and 22120025
- Volume :
- 15
- Issue :
- 4
- Database :
- Directory of Open Access Journals
- Journal :
- Indian Journal of Transplantation
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.98a1627538ec4250befe90376ec8755a
- Document Type :
- article
- Full Text :
- https://doi.org/10.4103/ijot.ijot_69_21