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GnRH-immunocastration: an alternative method for male animal surgical castration

Authors :
Chun Wang
Cuiting Yang
Yutian Zeng
Ming Zhang
Source :
Frontiers in Veterinary Science, Vol 10 (2023)
Publication Year :
2023
Publisher :
Frontiers Media S.A., 2023.

Abstract

Castration of male animals is intended to produce high-enhance quality of animal meat, prevent unpleasant taste, reduce aggressive behavior, and manage overbreeding. Over the years, Tranditional methods of mechanical and surgical castration have been employed over the years, but they fall short of meeting animal welfare requirements due to the associated risk of infection, pain, and stress. Immunocastration, specifically Gonadotropin-releasing hormone (GnRH)-immunocastration, targeting the hypothalamic–pituitary-testis (HPT) axis, has emerged as an animal-friendly alternative to surgical castration, effectively addressing these issues. This review seeks to systematically summarize the principles, development, current applications and challenges of GnRH-immunocastration, offering insights into its role in promoting animal welfare.

Details

Language :
English
ISSN :
22971769
Volume :
10
Database :
Directory of Open Access Journals
Journal :
Frontiers in Veterinary Science
Publication Type :
Academic Journal
Accession number :
edsdoj.9865fea652c94a4d8df31f6b7bcf54a5
Document Type :
article
Full Text :
https://doi.org/10.3389/fvets.2023.1248879