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Cortical arousal in children and adolescents with functional neurological symptoms during the auditory oddball task
- Source :
- NeuroImage: Clinical, Vol 13, Iss C, Pp 228-236 (2017)
- Publication Year :
- 2017
- Publisher :
- Elsevier, 2017.
-
Abstract
- Objective: Stress, pain, injury, and psychological trauma all induce arousal-mediated changes in brain network organization. The associated, high level of arousal may disrupt motor-sensory processing and result in aberrant patterns of motor function, including functional neurological symptoms. We used the auditory oddball paradigm to assess cortical arousal in children and adolescents with functional neurological symptom disorder. Method: Electroencephalogram (EEG) data was collected in fifty-seven children and adolescents (41 girls; 16 boys, aged 8.5–18 years) with acute functional neurological symptoms and age- sex- matched controls during a conventional auditory oddball task. The high-resolution fragmentary decomposition technique was used to analyse the amplitude of event-related potentials (ERPs) to target tones at midline sites (Fz, Cz, and Pz). Results: Compared to age- and sex-matched controls, and across all three midline sites, children and adolescents with functional neurological symptoms showed increased amplitude of all ERP components (P50, N100, P200, N200, and P300) (t-value range 2.28–8.20; p value-range 0.023 to
Details
- Language :
- English
- ISSN :
- 22131582
- Volume :
- 13
- Issue :
- C
- Database :
- Directory of Open Access Journals
- Journal :
- NeuroImage: Clinical
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.97e34b6384da4e329c6c393ec9c6e279
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.nicl.2016.10.016