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Deregulated over expression of FOXP1 protein in diffuse large B-cell lymphoma does not occur as a result of gene rearrangement
- Source :
- Haematologica, Vol 92, Iss 6 (2007)
- Publication Year :
- 2007
- Publisher :
- Ferrata Storti Foundation, 2007.
-
Abstract
- Strong uniform expression of FOXP1 protein occurs in a subgroup of non-germinal centre (GC) diffuse large B-cell lymphomas (DLBCL). We have investigated gene rearrangement as a potential mechanism for deregulated expression of FOXP1 however, using FISH FOXP1 translocations were not found in any case with over-expression of the protein.
- Subjects :
- Diseases of the blood and blood-forming organs
RC633-647.5
Subjects
Details
- Language :
- English
- ISSN :
- 03906078 and 15928721
- Volume :
- 92
- Issue :
- 6
- Database :
- Directory of Open Access Journals
- Journal :
- Haematologica
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.973da02aa64a3b9020a2a848c24883
- Document Type :
- article
- Full Text :
- https://doi.org/10.3324/haematol.10656