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Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer

Authors :
Myoung-Hee Kang
Hyunji Choi
Masanobu Oshima
Jae-Ho Cheong
Seokho Kim
Jung Hoon Lee
Young Soo Park
Hueng-Sik Choi
Mi-Na Kweon
Chan-Gi Pack
Ju-Seog Lee
Gordon B. Mills
Seung-Jae Myung
Yun-Yong Park
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Very little is known regarding the molecular mechanisms involved in gastric cancer development. Here the authors show estrogen-related receptor gamma (ESRRG) is a tumor suppressor in gastric cancer and suggest the mechanism of this tumor suppression function involves the inhibition of Wnt signaling.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.973b51c8851d4d10916c207ff982e196
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-04244-2