Back to Search
Start Over
Tenascin-C drives persistence of organ fibrosis
- Source :
- Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
- Publication Year :
- 2016
- Publisher :
- Nature Portfolio, 2016.
-
Abstract
- Systemic sclerosis (SSc) is a fibrotic disease affecting multiple organs. Here the authors use patient samples plus mouse studies to show a central role for tenascin C as a TLR4 activator responsible for persistence of fibrosis in the context of SSc and SSc-like disease.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 7
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.972eca9c0b4547b31a8d0ec137cae1
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/ncomms11703