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SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis

Authors :
Minhoo Kim
Yoonjung Choi
Harim Kim
Daeyoup Lee
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Stress-inducible transcripts are quickly exported to preserve cell survival when cells are under stress. Here, the authors suggest that Sgf73p of the SAGA deubiquitylating module monitors messenger ribonucleoprotein biogenesis to regulate non-canonical export of stress-inducible transcripts.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.96b862436bc4a378374a714644eafc6
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-10350-6