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Pruritus and Atopic Dermatitis: from Etiological Features to Management

Authors :
Nikolay N. Murashkin
Leonid A. Opryatin
Roman V. Epishev
Alexander I. Materikin
Eduard T. Ambarchian
Roman A. Ivanov
Dmitriy V. Fedorov
Daria S. Kukoleva
Source :
Вопросы современной педиатрии, Vol 19, Iss 6, Pp 468-476 (2020)
Publication Year :
2020
Publisher :
"Paediatrician" Publishers LLC, 2020.

Abstract

Pruritus is one of the main clinical manifestations of atopic dermatitis, and it significantly reduces the quality of life of patients in childhood. Scientific images on its pathophysiological basis have now undergone significant changes. The histamine exceptional role in pruritus development was confounded, as well as data on immune system involvement in its maintenance was given. This article presents current data on differential approaches to pruritus management depending on its etiopathogenetic characteristics. The role of dermocosmetics in restoration of the skin barrier as the first stage prevention of pruritus in atopic dermatitis was considered. The results of clinical studies showing efficacy of topical agents (innovative component with anti-pruritic action — STIMU-TEX) application are presented.

Details

Language :
English, Russian
ISSN :
16825527 and 16825535
Volume :
19
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Вопросы современной педиатрии
Publication Type :
Academic Journal
Accession number :
edsdoj.95ea216c4ddc440d95667b7c82e63da3
Document Type :
article
Full Text :
https://doi.org/10.15690/vsp.v19i6.2151