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Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C

Authors :
Juanjie Tang
Tanya Novak
Julian Hecker
Gabrielle Grubbs
Fatema Tuz Zahra
Lorenza Bellusci
Sara Pourhashemi
Janet Chou
Kristin Moffitt
Natasha B. Halasa
Stephanie P. Schwartz
Tracie C. Walker
Keiko M. Tarquinio
Matt S. Zinter
Mary A. Staat
Shira J. Gertz
Natalie Z. Cvijanovich
Jennifer E. Schuster
Laura L. Loftis
Bria M. Coates
Elizabeth H. Mack
Katherine Irby
Julie C. Fitzgerald
Courtney M. Rowan
Michele Kong
Heidi R. Flori
Aline B. Maddux
Steven L. Shein
Hillary Crandall
Janet R. Hume
Charlotte V. Hobbs
Adriana H. Tremoulet
Chisato Shimizu
Jane C. Burns
Sabrina R. Chen
Hye Kyung Moon
Christoph Lange
Adrienne G. Randolph
Surender Khurana
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

The antibody response to the SARS-CoV-2 Omicron variant is not well studied in children. Here, the authors provide an age-stratified analysis of SARS-CoV-2 neutralizing capacity of sera from children with acute or convalescent COVID-19 as well as children with multisystem inflammatory syndrome.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.95d32cb646c4ee9abe90f1a0721b0aa
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-30649-1