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A systematic review and meta-analysis on blood levels of cytokines/chemokines in COVID-19 cases
- Source :
- Gülhane Tıp Dergisi, Vol 64, Iss 3, Pp 208-216 (2022)
- Publication Year :
- 2022
- Publisher :
- Galenos Publishing House, 2022.
-
Abstract
- We assessed the blood levels of the most important factors such as cytokines/chemokines in Coronavirus disease-2019 (COVID-19). PubMed/Medline and Scopus as two important databases were searched up to March 26, 2020. To analyze the data, we used Review Manager 5.3 software. Out of forty-two records retrieved from two databases, 10 studies were involved in the analysis. Thirty-three cytokines/chemokines were checked. The levels of 27 cytokines/chemokines in COVID-19 patients were higher than the healthy controls, and among 20 cytokines/chemokines; the levels of 10 cytokines/chemokines in severe COVID-19 patients were higher than non-severe COVID-19 patients. Also, out of three cytokines, one had a higher level in the intensive care unit (ICU) patients compared to the non-ICU patients. The findings showed the cytokine storm syndrome in COVID-19 patients, especially in patients with severe disease.
Details
- Language :
- English
- ISSN :
- 21468052
- Volume :
- 64
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Gülhane Tıp Dergisi
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.952a904b7b2f45dab593f21da2b8f7c6
- Document Type :
- article
- Full Text :
- https://doi.org/10.4274/gulhane.galenos.2021.25733