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Chemical Constituents from Euphorbia kansui

Authors :
Qiao Zhang
Qin-Rong Zhou
Jian-Wei Lou
Pei-Dong Chen
Wei-Feng Yao
Wei-Wei Tao
Yu-Ping Tang
Guan-Cheng Dai
Kun Wang
Li Zhang
Source :
Molecules, Vol 22, Iss 12, p 2176 (2017)
Publication Year :
2017
Publisher :
MDPI AG, 2017.

Abstract

In this research, a new triterpenoid, tirucalla-8,24-diene-3β,11β-diol-7-one (1), and eupha-8,24-diene-3β,11β-diol-7-one (2), which was isolated from Euphorbia kansui for the first time, together with twelve other known compounds (3–14), were isolated from the ethyl acetate extract of Euphorbia kansui. Their structures were elucidated based on High resolution electrospray ionization mass spectrometry (HR-ESI-MS), Infrared Spectroscopy (IR), 1D and 2D Nuclear Magnetic Resonance (NMR) data. Both constituents 1 and 2 exhibited moderate cytotoxicity against colon cancer HCT-116, gastric cancer MKN-45 and breast cancer MCF-7.

Details

Language :
English
ISSN :
14203049 and 22122176
Volume :
22
Issue :
12
Database :
Directory of Open Access Journals
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
edsdoj.94bf9dd837a844caa832046fdfb9f9bc
Document Type :
article
Full Text :
https://doi.org/10.3390/molecules22122176