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SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice
- Source :
- Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Portfolio, 2022.
-
Abstract
- The protein SLITRK2 plays an important role in synaptic communication. This study identifies X-linked SLITRK2 variants that underlie neurodevelopmental disorders by impairing excitatory synapses.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723 and 80364845
- Volume :
- 13
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.939b1e803648458f978aa0c525329996
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-022-31566-z