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Conservation laws by virtue of scale symmetries in neural systems.

Authors :
Erik D Fagerholm
W M C Foulkes
Yasir Gallero-Salas
Fritjof Helmchen
Karl J Friston
Rosalyn J Moran
Robert Leech
Source :
PLoS Computational Biology, Vol 16, Iss 5, p e1007865 (2020)
Publication Year :
2020
Publisher :
Public Library of Science (PLoS), 2020.

Abstract

In contrast to the symmetries of translation in space, rotation in space, and translation in time, the known laws of physics are not universally invariant under transformation of scale. However, a special case exists in which the action is scale invariant if it satisfies the following two constraints: 1) it must depend upon a scale-free Lagrangian, and 2) the Lagrangian must change under scale in the same way as the inverse time, [Formula: see text]. Our contribution lies in the derivation of a generalised Lagrangian, in the form of a power series expansion, that satisfies these constraints. This generalised Lagrangian furnishes a normal form for dynamic causal models-state space models based upon differential equations-that can be used to distinguish scale symmetry from scale freeness in empirical data. We establish face validity with an analysis of simulated data, in which we show how scale symmetry can be identified and how the associated conserved quantities can be estimated in neuronal time series.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
1553734X and 15537358
Volume :
16
Issue :
5
Database :
Directory of Open Access Journals
Journal :
PLoS Computational Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.938b7cd2d8494086b9c76c740a0189a8
Document Type :
article
Full Text :
https://doi.org/10.1371/journal.pcbi.1007865