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Prospective Validation of Glial Fibrillary Acidic Protein, d‐Dimer, and Clinical Scales for Acute Large‐Vessel Occlusion Ischemic Stroke Detection
- Source :
- Stroke: Vascular and Interventional Neurology, Vol 4, Iss 4 (2024)
- Publication Year :
- 2024
- Publisher :
- Wiley, 2024.
-
Abstract
- Background Large‐vessel occlusion (LVO) ischemic stroke is responsible for significant morbidity and mortality. We have previously described a novel tool for acute LVO detection that combines blood‐based biomarkers (glial fibrillary acidic protein and d‐dimer) with stroke severity scales to achieve high accuracy. Accordingly, the present study sought to prospectively validate cutoff values that we had previously established for biomarkers and scales. Methods The TIME (Testing for Identification Markers of Stroke) trial was designed as a prospective observational diagnostic accuracy study. All ambulance‐identified stroke code activations
Details
- Language :
- English
- ISSN :
- 26945746
- Volume :
- 4
- Issue :
- 4
- Database :
- Directory of Open Access Journals
- Journal :
- Stroke: Vascular and Interventional Neurology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.933c25860f4c98b046fd01360e10dc
- Document Type :
- article
- Full Text :
- https://doi.org/10.1161/SVIN.123.001304