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Three years’ interventional neurology experience in Turkey with the Thrombite thrombectomy device in large vessel occlusion in the anterior circulation: safety, efficacy, and clinical outcome

Authors :
Çetin Kürşad Akpınar
Erdem Gurkas
Atilla Ozcan Ozdemir
Hasan Doğan
Ayşenur Önalan
Serhan Yıldırım
Zülfikar Memiş
Emrah Aytaç
Bilgehan Atılgan Acar
Muhammed Nur Öğün
Özlem Aykaç
Zehra Uysal Kocabaş
Türkan Acar
Halil Alper Eryılmaz
Berkhan Topaktaş
Source :
Frontiers in Neurology, Vol 15 (2024)
Publication Year :
2024
Publisher :
Frontiers Media S.A., 2024.

Abstract

IntroductionWhile the Thrombite device differs from the Solitare stent with its Helical open-side structure feature, it shows great similarity with its other features. We assessed the Thrombite device’s effectiveness and safety in this study.Materials and methodsThe study was a retrospective analysis of patients who were included in the Turkish Interventional Neurology database and who had mechanical thrombectomy with the Thrombite device as the first choice between January 2020 and January 2023. The type of study is descriptive research.ResultUsing the Thrombite thrombectomy device, 525 patients received treatment. The median baseline National Institutes of Health Stroke Scale (NIHSS) score was 13, the median initial Alberta Stroke Program Early Computed Tomography (ASPECT) score was 8, and the mean patient age was 68.6+11.7 years. Between the groin puncture and the successful recanalization, the median time was 34 minutes (interquartile range [IQR]: 15–45). 48.2% (modified treatment in cerebral infarction; mTICI) 2b/3% and 33.9% (mTICI 2c/3) were the first-pass recanalization rates. In the end, 87.7% of patients had effective recanalization (thrombolysis in cerebral infarction 2b/3). In the “first-pass” subgroup, the favorable functional result (modified Rankin Scale 0–2) was 51.8%, while it was 41.6% for the entire patient population. The rate of embolization into new territory/different territory were 2.1/0.1%. 23 patients (4.5%) had symptomatic hemorrhage.ConclusionThe Thrombite device showed a good safety profile and high overall successful recanalization rates in our experience.

Details

Language :
English
ISSN :
16642295
Volume :
15
Database :
Directory of Open Access Journals
Journal :
Frontiers in Neurology
Publication Type :
Academic Journal
Accession number :
edsdoj.92f0f4d645c64bcd9c82e16ec5033abb
Document Type :
article
Full Text :
https://doi.org/10.3389/fneur.2024.1320510