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Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments
- Source :
- Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
- Publication Year :
- 2021
- Publisher :
- Nature Portfolio, 2021.
-
Abstract
- The mechanics of the migration of T cells into tumours is an important aspect of tumour immunity. Here the authors engineer complex 3D environments to explore functions of microtubules and cell contractility as strategies to enhance T cell migration in tumour microenvironments.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723 and 06966543
- Volume :
- 12
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.9258c06966543cda042cc7df55119b0
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-021-22985-5