Back to Search Start Over

Molecular characterization of breast cancer CTCs associated with brain metastasis

Authors :
Debasish Boral
Monika Vishnoi
Haowen N. Liu
Wei Yin
Marc L. Sprouse
Antonio Scamardo
David S. Hong
Tuan Z. Tan
Jean P. Thiery
Jenny C. Chang
Dario Marchetti
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

Characterization of CTCs derived from breast cancer patients with brain metastasis (BCBM) may allow for early diagnosis of brain metastasis and/or help for treatment choice and its efficacy. In this study, the authors identify a unique signature, based on patient-derived CTCs transcriptomes, for BCBM- CTCs that is different from primary tumors.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.924c0ac03d9d404c931127a48b58fb79
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-00196-1