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Diabetic foot ulcers treatment with silver nanoparticles
- Source :
- Revista de Ciencias Tecnológicas, Vol 2, Iss 1 (2019)
- Publication Year :
- 2019
- Publisher :
- Universidad Autónoma de Baja California, 2019.
-
Abstract
- Diabetic foot ulcers are highly susceptible to microbial infections and are the leading cause of lower limb hospitalization and amputation in diabetic patients. Due to their antimicrobial and anti-inflammatory properties, silver nanoparticles (AgNPs) are the most widely used nanomaterial in biomedicine. Herein, we present the usage of AgNPs for the treatment of diabetic foot ulcers with a stage II in Wagner classification. In addition to conventional antibiotic treatment, the ulcers were treated with topical administration of AgNPs at a concentration of 1.2 mg/ml of metallic silver. The results showed a significant improvement in the evolution of the ulcers, where the edges of the lesion were effectively approached, granulation tissue being observed, edema decreased and fibrin plaques. These results form the basis for further studies on the use of AgNPs for the treatment of chronic ulcers of different origins.
Details
- Language :
- English, Spanish; Castilian
- ISSN :
- 25941925
- Volume :
- 2
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Revista de Ciencias Tecnológicas
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.923b0d5665c84c18870dd7d739ac5cc8
- Document Type :
- article
- Full Text :
- https://doi.org/10.37636/recit.v212025