Back to Search Start Over

IRON DEPOSITION IN THE GROWTH PLATE OF LONG BONES OF THE OFFSPRING WHEN GIVEN DURING PREGNANCY IN RAT MODEL

Authors :
Faiza Umbreen
Khadija Qamar
Sadia Shaukat
Maimoona Khan
Sana Malik
Hussain Ali
Source :
Pakistan Armed Forces Medical Journal, Vol 71, Iss 4, Pp 1223-26 (2021)
Publication Year :
2021
Publisher :
Army Medical College Rawalpindi, 2021.

Abstract

Objective: To evaluate histologically the deposition of iron in the epiphyseal cartilage of offspring’s of dams given iron supplementation during pregnancy and lactation in rat model. Study Design: Laboratory based experimental study. Place and Duration of Study: Department of Anatomy, Army Medical College, Rawalpindi and National Institute of Health (NIH) Islamabad, from Mar to Nov 2016. Methodology: In this study, 16 female and 4 male adult rats were chosen for breading. After confirmation of pregnancy, pregnant rats were separated in two groups. One group was given oral iron supplementation for four weeks till delivery and half of the pups fed by mothers who were given iron during lactation. The other group was kept on normal lab diet. Deposition of iron in the epiphyseal cartilage of newborn rats after four weeks was evaluated histologically in pups. Results: Iron deposition was maximum in group C i.e. 1.30 ± 0.48; in group B it was 0.20 ± 0.44. Statistically significant iron deposition (p

Details

Language :
English
ISSN :
00309648 and 24118842
Volume :
71
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Pakistan Armed Forces Medical Journal
Publication Type :
Academic Journal
Accession number :
edsdoj.9223174eda414dcf8f99a4b1973b7993
Document Type :
article
Full Text :
https://doi.org/10.51253/pafmj.v71i4.4103