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Regulation of Drosophila hematopoietic sites by Activin-β from active sensory neurons

Authors :
Kalpana Makhijani
Brandy Alexander
Deepti Rao
Sophia Petraki
Leire Herboso
Katelyn Kukar
Itrat Batool
Stephanie Wachner
Katrina S. Gold
Corinna Wong
Michael B. O’Connor
Katja Brückner
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

Hematopoietic sites in theDrosophilalarva require the local peripheral nervous system for blood cells (hemocytes) to survive and proliferate, but how this is mediated is unclear. Here, the authors identify Activin-β from sensory neurons as signalling to hemocytes, affecting proliferation and adhesion.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.9187e1f8cb4f4d59831554b315e0c04e
Document Type :
article
Full Text :
https://doi.org/10.1038/ncomms15990